This presentation work by Hau-Ping Chou, Tang-Kai Wang, Yu-Ting Huang, Tze-Chung Huang, shows achievement and development of Bio-pesticides in Chinese Taipei. It is the case study of Bacillus amyloliquefaciensPMB01 of agricultural research and extension station. Country paper show Autochthonous bio- pesticides research, registration and commercial- lization in R.O.C. and shard the management system of bio-pesticides registration in R.O.C. In the case of Autochthonous bio- pesticides research, BaPMB01 can be applied as organic materials for controlling crop diseases, and further reduce the usage of chemical pesticides in the field.